Welcome to the Translational Retinal Research Laboratory

Our lab advances the frontiers of retinal medicine through state-of-the-art research and multi-disciplinary approach, developing next-generation therapeutics for retinal degenerative diseases and innovative tools to improve vitreo-retinal surgery outcomes.

Our work focuses on three areas:

Enhancing Retinal Stem Cell Survival in-vivo

Our research develops hypo-immunogenic cord-lining derived iPSCs and novel scaffolds for retinal cell replacement therapy in age-related macular degeneration (AMD). We complement this with single-cell omics technologies to understand retinal micro-environment biology and the cellular pathways governing homeostasis and disease.

Discovering Retinal Therapeutics

We are establishing comprehensive disease modelling platforms using large patient cohorts and biobanks for AMD and inherited retinal dystrophies (IRD). Patient-specific iPSC-derived retinal cells and organoids recapitulate human retinal diseases, enabling us to study disease mechanisms and test therapeutic interventions. Using these foundational datasets, we are developing AI-driven computational approaches to accelerate the discovery of safer and more effective retinal therapeutics.

Developing tools for Retinal Stem Cell Transplant

We develop innovative vitreo-retinal surgical techniques using advanced in-vivo modeling at our specialized ophthalmic surgical suite. We are also advancing our patented biocompatible thermosensitive hydrogel, Vitreogel™, toward clinical trials, while expanding this biomaterial platform for sustained ocular drug delivery systems and advanced polymer-based scaffolds to support stem cell transplantation and retinal tissue engineering.

Find out more about our Research Focus.